What Happens When You Mix Your Medication With CBD?

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CBD Instead is very passionate about using our products correctly and safely. The purpose of hemp oil is to heal and help, and we recognize this isn’t so for everyone. You know who knows what is best for you nine times out of 10? Your doctor. You should always keep them in the loop when putting any chemicals in your body, regardless if they have shown to be nothing but helpful in so many others.

This is especially true if you are taking medication, so let's talk about mixing medicine with CBD. If you are already putting chemicals into your body to fix something, adding CBD just turns your regimen into a random cocktail if you don’t know how they react together. It is never a good idea to play brain chemist by yourself because you never know if you might accidentally do something that can’t be undone.  It might be wise to begin your journey with our Beginner's Guide to CBD prior to scrolling down.

Mixing CBD with Medicine

Medication That May Cause Adverse Effects

There is a family of isozymes responsible for the biotransformation of some medications called Cytochrome P-450. CBD interacts with these prescription pills by inhibiting this enzyme system. When you are prescribed a particular medication, the doctor takes into account how fast your body will process the medicine to figure out the right dosage for you and your body.  If it changes making the pill digest faster or slower, it can create adverse reactions.

Drugs Processed By Cytochrome P-450

  • Beta Blockers
  • Proton Pump Inhibitors
  • Steroids
  • Anesthetics
  • Macrolide Antibiotics
  • Anti-Arrhythmics
  • Benzodiazepines
  • Oral Hypoglycemic Agents
  • Antidepressants
  • Anti-eleptics
  • Angiotensin II Blockers
  • Sulfonylureas
  • Antipsychotics
  • Immune Modulators
  • HIV Antivirals
  • Antihistamines
  • Prokinetic
  • Calcium Channel Blockers

For a full list, here is a drug interaction table with the full list of medications that are processed by Cytochrome P-450 enzymes.

Does This Mean You Can’t Take CBD?

This is where your doctor comes in. There are a lot of reasons to take CBD and still need to take your prescriptions, even though half of the people who try CBD drop their prescriptions altogether. Explain to your doctor why you think you need to take CBD and the concerns you have with how it may affect your medication. First of all, your doctor will be impressed. Second, your doctor can adjust your medication to work with CBD, or they can work with you to figure out a good regimen for getting you happy and healthy.

Once you’ve figured it out and you can start your journey towards a healthier future, check out our shop! We have a great variety of ways to take CBD to fit almost anyone’s comfort level. Whether you like to smoke it, eat it, or drop it, CBD Instead has got you covered.

Sarah Potts


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